Room Service is centered around a theatrical producer of questionable morals, holed up in a Times Square hotel with 19 starving actors, as he attempts to rehearse and find backers for his new show. Hoping to forestall eviction, he convinces the gullible young playwright to fake his own death. Meanwhile, an emissary from one of the country's wealthiest businessmen turns up with money to invest in the show; that is, until he discovers the hotel doctor bound and gagged in the bathroom. The situation goes from bad to worse as the much-abused hotel manager threatens to have the entire show confiscated by the sheriff on opening night!