Malone is best known for her film work. Her big screen credits include the latest Pride and Prejudice remake, The Ballad of Jack and Rose, Saved, United States of Leland, Cold Mountain, Corn, American Girl, The Badge, Life as a House, Donnie Darko, Dangerous Lives of Altar Boys, Cheaters, For the Love of the Game, Book of Stars, Stepmom and Contact. Her television credits include the made-for-TV movies Hope for which she received a Golden Globe nomination and Bastard Out of Carolina with Eldard.