Margulies is probably best known for her Emmy Award-winning portrayal of Nurse Carol Hathaway on the hit drama ER. During her six seasons on the show, she was nominated for four Outstanding Lead Actress in a Drama Series Emmys and two Outstanding Supporting Actress in a Drama Series Emmys, winning one in the latter category. Margulies previously appeared in Intrigue With Faye at NY Stage and Film. She won a 2001 Lucille Lortel Award for Outstanding Featured Actress for her performance in the Lincoln Center production of Ten Unknowns. She was seen off-Broadway in The Vagina Monologues she also appeared in the Los Angeles production of that show and Intrigue with Faye. Her other stage credits include Fefu and her Friends, The Substance of Fire, Living Expenses, Book of Names, Balm in Gilead and In the Boom Boom Room. Her film credits include A Price Above Rubies, Evelyn and Ghost Ship. She was nominated for a 2004 Golden Globe Award for her performance in the television miniseries The Grid, which had six installments on TNT last year.
Late Fragments tells the story of a man Rispoli who miraculously survives the collapse of the World Trade Center and returns home to his wife Marguiles to find that his life is not at all what he thought it was.
The show will feature sets and costumes by Victoria Imperioli, who heads Studio Dante with her husband.